Chlorpromazine and dimethyl sulfoxide modulate the catalytic activity of the plasma membrane Ca2+-ATPase from human erythrocyte

The plasma membrane Ca2+-ATPase (PMCA) removes Ca2+ from the cytosol into the extracellular space. Its catalytic activity can be stimulated by calmodulin (CaM) or by limited proteolysis. We evaluated the effect of chlorpromazine (CPZ) and dimethyl sulfoxide (DMSO) over the hydrolytic activity of PMC...

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Glavni avtor: Plenge, Luis
Drugi avtorji: Domínguez-Solís, Carlos A., Díaz-Sánchez, Ángel G., Meléndez Martínez, David, Vargas-Medrano, Javier, Sierra-Fonseca, Jorge A.
Format: Artículo
Jezik:en_US
Izdano: Springer US 2018
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Online dostop:https://doi.org/10.1007/s10863-017-9741-9
https://link.springer.com/article/10.1007%2Fs10863-017-9741-9
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