pH-responsive polymer micelles for methotrexate delivery at tumor microenvironments

Methotrexate (MTX) anticancer drug was successfully loaded and released in a controlled manner from polymer micelles made of a diblock copolymer of poly(monomethoxy ethylene glycol)-b-poly(ε-caprolactone) (mPEG-PCL). The empty and MTX-loaded micelles (MTX/mPEG-PCL) were characterized by electron...

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主要作者: Castro Carmona, Javier Servando
其他作者: Carrillo Castillo, Teresa Darlen, Luna Velasco, Antonia, Zaragoza Contreras, Armando Erasmo
格式: Artículo
语言:English
出版: 2020
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在线阅读:https://doi.org/10.1515/epoly-2020-0064
https://doi.org/10.1515/epoly-2020-0064
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